Pathology EMQ template.

Name: Aubrey Smith

Candidate number:

Theme: Stem Cell Transplantation

OPTION LIST

A	Veno-Occlusive Disease	I	Fanconi’s Anaemia
B	GVHD	J
C	Neuroblastoma	K
D	Amyloidosis	L
E	Hodgkins Lymphoma	M
F	Sickle Cell Anaemia	N
G	Transplantation Related Lung Injury	O
H	CML	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. This is an early complication arising from HSCT characterized by ascites, hyperbilirubinaemia and weight gain. It is caused by damage to the sinusoidal epithelium.

2. This is an autosomal recessive disorder with increased susceptibility to AML and is treated with allogeneic transplantation.

3. This is a malignant condition which can be treated with allogeneic or autologous transplantation and is characterized histologically by the presence of Reed- Sternberg cells.

4. This is an acute inflammatory response that leads to severe tissue injury seen after allogeneic tranplants.

5. This is a non malignant disorder characterized by extracellular deposits of an abnormal degradation-resistent protein and is detected by Congo red staining. It is treated with autologous transplantation

ANSWERS

1. A

2. I

3. E

4. G

5. D